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Our Partnering Services

Top 10 Reasons to Partner with Zenobia Therapeutics

10. We have over 100 entries in the PDB, have purified over 100 unique proteins and have over 100 years combined experience in protein crystallography, FBLD and SBDD.
9. We are co-inventors/pioneers in the fields of both NMR and x-ray crystallographic fragment screening (Shuker et al., Science 1996; Nienaber et al., Nature Biotechnology, 2000).
8. We have hands-on drug discovery experience at small and large pharmaceutical and several biotechnnology firms.
7. We have managed successful partnerships ranging from $100,000 to tens of millions.
6. We have a fully equipped facility for high-throughput cloning and expression in both E coli and baculovirus.
5. We have customized vectors to maximize diversity not only in the constructs we pursue but the tags and expression systems used to produce them.
4. We purify and crystallize challenging targets including soluble and membrane associated proteins.
3. We have automated structure determination programs which allow rapid data processing and conversion to high-resolution x-ray structures for co-crystal structure analysis and FBLD.
2. We have routine access to third generation synchrotrons year-round allowing high-quality fast-turn around data collection.
1. Big things come in small packages: A century of experience combined with the personalized service, flexibility and responsiveness of a small company.

info@zenobiatherapeutics.com

858-926-5780

 
 Custom Library Design
  • General screening libraries
  • Follow-on libraries
  • Targeted libraries

(acquisition, plating and shipment included)

 

 Fragment-based Screening
  • Biochemical assays
  • SPR
  • X-Ray crystallography
  • Proprietary methods upon request

 

 Structural Biology
  • Full gene to structure
  • Co-crystallization
  • Data analysis
  • Structure building